Multidrug resistance in Salmonella isolates of swine origin: mobile genetic elements and plasmids associated with cephalosporin resistance with potential transmission to humans

The emergence of foodborne Salmonella strains carrying antimicrobial resistance (AMR) in mobile genetic elements (MGE) is a significant public health threat, particularly in a One Health context. A study of 83 strains from pigs in Northern Spain revealed that all isolates were susceptible to ciprofloxacin and three had blaCMY-2 or blaCTX-M-9 genes responsible for cefotaxime resistance. The study emphasizes the importance of sequencing techniques to identify emerging AMR regions in conjugative and stable plasmids from livestock production.